SURGICAL TREATMENT OF EXTENDED PHLEGMONUS IN COMBINATION WITH SYSTEMIC OZONE THERAPY

Abstract

Objectives. This article aims to review current concepts regarding the surgical treatment of extensive phlegmon in combination with systemic ozone therapy.

Methods. This systematic review was conducted based on articles, scientific research, clinical studies of necrotic-purulent pathology as well as the use of ozonetherapy in the treatment of this pathology, over several years on platforms such as PubMed, Scopus and Web of Science, and the keywords entered were “extended phlegmon”, “ozonotherapy”, “systemic ozonetherapy”, which include contemporary data on the etiology, pathophysiology, epidemiology, classification and diagnosis of patients with extended phlegmon in combination with systemic ozone therapy.

Results. From the list of surgical diseases, extensive phlegmon accounts for approximately 5.9% with a very high mortality rate, which varies according to literature data from 20% to 40%. Most cases are found in young men. Of those mentioned, approximately 60-70% of cases are in people of working age between 40 and 60, thus representing a real social and economic problem, and the economic impact of this condition is significant, as approximately 70% of patients are completely unable to work for up to 2 years and at least partially affected for up to 4 years after surgery, with most of them obtaining a severe disability rating. This review of the literature evaluated the results of the use of complex associated treatment in patients suffering from extensive necrotic-purulent pathology, resulting in major tissue loss, and determined the role of systemic ozone therapy in the regeneration of these wounds.

Conclusions. Studying the literature data, the results of the use of complex medical and surgical treatment of extensive phlegmon resulting in tissue loss are evaluated, and the effectiveness of systemic ozone therapy in the evolution of this pathology is estimated, with the establishment of indications and contraindications, as well as the optimal terms for its implementation in the evolution of the wound regeneration process, with a reduction in hospitalization time, complication rates and hospital mortality.