EVOLUTION OF THERAPEUTIC APPROACH IN CHRONIC SKIN ULCERS

Abstract

Objectives. The treatment of chronic skin ulcers is a current problem, both in terms of frequency and the complexity of the social and economic consequences they involve. The aim of study was to analyze the specialized medical literature about the evolution of therapeutic approaches in chronic skin ulcers.

Materials and methods. The most relevant recommendations related to the treatment of chronic skin ulcers, selected from international databases, such as: PubMed Central, PubMed, Medline, ScienceDirect, Google Scholar, NCBI and UpToDate have been accessed and analyzed, by using keywords: ”chronic skin ulcers”, ”history”, ”treatment evolution”.

Results and discussions. The study highlights that conservative therapy of skin ulcers aims at proper tissue preparation, infection control, wound moisture maintenance and epidermal growth stimulation, being a difficult and expensive process. It is important to identify the primary causes that have led to the development of ulcer and to choose the best option of conservative therapy, which has non-toxic, non-allergic properties, increases the comfort of the maintenance and reduces the duration of hospitalization, treatment costs, ensuring a faster recovery of patients to daily activities.

Conclusions. Wound healing is a complex, highly regulated process that is critical in maintaining the barrier function of skin. During the last years, the management of chronic skin ulcers have evolved considerably, approaching the major interfering factors of normal healing process, which will help patients and wound care practitioners largely.