NECROZA PANCREATICĂ ÎN BOLILE TERMINALE FĂRĂ IMPACT CHIRURGICAL

Sergiu Revencu; Alexandru Gaitur; Ruslan Pretula; Ion Garștea; Sergiu Balan; Dan Revencu; Eugeniu Beschieru; Ion Crăciun

doi:10.5281/zenodo.13328393

Authors

Sergiu Revencu Surgery Department no. 1 „Nicolae Anestiadi”, State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Chișinău, Republic of Moldova
Alexandru Gaitur Municipal Clinical Hospital "Sfântul Arhanghel Mihail", Chișinău, Republic of Moldova
Ruslan Pretula Department of Morphopathology, "Nicolae Testemițanu" State University of Medicine and Pharmacy, Chisinau, Republic of Moldova
Ion Garștea Municipal Clinical Hospital "Sfântul Arhanghel Mihail", Chișinău, Republic of Moldova
Sergiu Balan FHS ”Galaxia”, Chişinău, Republic of Moldova
Dan Revencu FHS ”Galaxia”, Chişinău, Republic of Moldova
Eugeniu Beschieru Surgery Department no. 1 „Nicolae Anestiadi”, State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Chișinău, Republic of Moldova
Ion Crăciun Surgery Department no. 1 „Nicolae Anestiadi”, State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Chișinău, Republic of Moldova

DOI:

https://doi.org/10.5281/zenodo.13328393

Keywords:

pancreatic necrosis, terminal diseases, morphopathology

Abstract

Objectives. Pancreatic necrosis are encountered incidentally during the anatomopathological examination in terminal non-surgical conditions. Elucidation of their frequency, morphological aspects, and background pathologies constituted the purpose of the given study.

Methods. From anatomopathological investigation protocols, collected from Municipal Clinical Hospital ”Saint Arhanghel Mihail”, during 2014 – 2020, of 550 cases of death, caused by diseases, in case of patients who did not undergo surgery, were selected 198 (36%) cases with which included changes at the pancreatic level, confirmed morphologically. Subsequently, the clinical observation sheets of these patients were also examined.

Results. The obtained morphological results highlighted: a) extensive pancreatic necrosis; b) focal pancreatic necrosis on the background of healthy pancreas; c) focal pancreatic necrosis on the background of chronic pancreatitis; d) pancreatic autolysis. In the cases of terminal diseases, liver cirrhosis predominated, followed by degenerative cardio-pulmonary diseases, cancer, inflammatory diseases mainly of the lungs, and diabetes.

Conclusions. In serious, terminal cases, in which death occurs after a long period, it is attested, both diffuse and localized pancreatic necrosis occur with obscure symptoms.